Sertraline 100mg: Cost, Savings, and How to Pay Less
Sertraline 100mg is the maximum standard dose SSRI antidepressant, with a Drug Tariff price of approximately 82p per pack.
How much does Sertraline 100mg cost on the NHS?
Sertraline 100mg has a Drug Tariff price of approximately 82p for a 28-tablets pack — a full month's supply. Yet NHS patients in England pay a flat £9.90 per item. With 23m items dispensed in 2024/25, Sertraline is one of the most prescribed drugs in England. Through RepeatsDirect, patients can access the same medication privately for £5.50/month.
How much does Sertraline 100mg actually cost?
The NHS Drug Tariff lists the reimbursement price for Sertraline 100mg at approximately 82p per 28-tablets pack. This is the price the NHS pays pharmacies for the drug itself. The NHS prescription charge of £9.90 covers this drug cost plus dispensing fees, administration, and a contribution to NHS services — but for cheap generic drugs, it represents a significant markup.
Drug Tariff cost
82p
per pack
NHS charge
£9.90
1,107% markup
Our price
£5.50
via private Rx
Sertraline has approximately 23m items dispensed annually in England (NHSBSA PCA 2024/25).
What is Sertraline used for?
Sertraline 100mg is a higher dose used when 50mg does not achieve adequate response. It can also be prescribed for OCD, which often requires higher doses than depression. The 100mg dose is widely used and well-tolerated.
The Drug Tariff price for Sertraline 100mg is approximately 82p per 28-tablet pack. The NHS prescription charge of £9.90 is 12 times the drug cost.
RepeatsDirect can supply Sertraline 100mg for £5.50 per month via private prescription, saving patients £4.40 per month versus the NHS charge.
How can you save money on Sertraline 100mg?
Patients in England who pay the prescription charge can switch to a private prescription for Sertraline 100mg and pay significantly less. Through RepeatsDirect, a qualified pharmacist independent prescriber conducts a short clinical review and issues a private prescription. You pay £5.50 per month — saving £4.40 per month, or £52.80 per year.
| Option | Per month | Per year |
|---|---|---|
| NHS prescription charge | £9.90 | £118.80 |
| RepeatsDirect (private Rx) | £5.50 | £66.00 |
| Annual PPC (unlimited NHS Rx) | £9.54/mo avg | £114.50 |
A PPC is better value if you pay for 12+ items per year. RepeatsDirect is better value if you pay for fewer items or only want to switch the cheapest drugs.
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