Omeprazole 40mg: Cost, Savings, and How to Pay Less
Omeprazole 40mg is a high-dose PPI for severe acid conditions and ulcer healing, with a Drug Tariff price of approximately 85p per pack.
How much does Omeprazole 40mg cost on the NHS?
Omeprazole 40mg has a Drug Tariff price of approximately 85p for a 28-capsules pack — a full month's supply. Yet NHS patients in England pay a flat £9.90 per item. With 36m items dispensed in 2024/25, Omeprazole is one of the most prescribed drugs in England. Through RepeatsDirect, patients can access the same medication privately for £5.50/month.
How much does Omeprazole 40mg actually cost?
The NHS Drug Tariff lists the reimbursement price for Omeprazole 40mg at approximately 85p per 28-capsules pack. This is the price the NHS pays pharmacies for the drug itself. The NHS prescription charge of £9.90 covers this drug cost plus dispensing fees, administration, and a contribution to NHS services — but for cheap generic drugs, it represents a significant markup.
Drug Tariff cost
85p
per pack
NHS charge
£9.90
1,065% markup
Our price
£5.50
via private Rx
Omeprazole has approximately 36m items dispensed annually in England (NHSBSA PCA 2024/25).
What is Omeprazole used for?
Omeprazole 40mg is a high dose used for severe oesophagitis, Zollinger-Ellison syndrome, and resistant peptic ulcers. It provides maximum acid suppression and is also used as part of H. pylori eradication therapy.
The Drug Tariff price for Omeprazole 40mg is approximately 85p per 28-capsule pack. The NHS charge of £9.90 is nearly 12 times the drug cost.
RepeatsDirect can supply Omeprazole 40mg privately for £5.50 per month following a pharmacist independent prescriber review.
How can you save money on Omeprazole 40mg?
Patients in England who pay the prescription charge can switch to a private prescription for Omeprazole 40mg and pay significantly less. Through RepeatsDirect, a qualified pharmacist independent prescriber conducts a short clinical review and issues a private prescription. You pay £5.50 per month — saving £4.40 per month, or £52.80 per year.
| Option | Per month | Per year |
|---|---|---|
| NHS prescription charge | £9.90 | £118.80 |
| RepeatsDirect (private Rx) | £5.50 | £66.00 |
| Annual PPC (unlimited NHS Rx) | £9.54/mo avg | £114.50 |
A PPC is better value if you pay for 12+ items per year. RepeatsDirect is better value if you pay for fewer items or only want to switch the cheapest drugs.
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