RepeatsDirect
💊Acid Reflux (PPIs)

Omeprazole 20mg: Cost, Savings, and How to Pay Less

Omeprazole 20mg is the standard-dose PPI for acid reflux and stomach protection, with a Drug Tariff price of approximately 70p per pack.

How much does Omeprazole 20mg cost on the NHS?

Omeprazole 20mg has a Drug Tariff price of approximately 70p for a 28-capsules pack — a full month's supply. Yet NHS patients in England pay a flat £9.90 per item. With 36m items dispensed in 2024/25, Omeprazole is one of the most prescribed drugs in England. Through RepeatsDirect, patients can access the same medication privately for £5.50/month.

How much does Omeprazole 20mg actually cost?

The NHS Drug Tariff lists the reimbursement price for Omeprazole 20mg at approximately 70p per 28-capsules pack. This is the price the NHS pays pharmacies for the drug itself. The NHS prescription charge of £9.90 covers this drug cost plus dispensing fees, administration, and a contribution to NHS services — but for cheap generic drugs, it represents a significant markup.

Drug Tariff cost

70p

per pack

NHS charge

£9.90

1,314% markup

Our price

£5.50

via private Rx

Omeprazole has approximately 36m items dispensed annually in England (NHSBSA PCA 2024/25).

What is Omeprazole used for?

Omeprazole 20mg is the standard dose for treating acid reflux, oesophagitis, and preventing stomach ulcers in patients taking NSAIDs. It is one of the most prescribed drugs in England, with over 36 million items dispensed annually. Omeprazole is also available without prescription at pharmacies.

The Drug Tariff price for Omeprazole 20mg is approximately 70p per 28-capsule pack. The NHS charge of £9.90 is 14 times the drug cost.

Through RepeatsDirect, patients can access Omeprazole 20mg via private prescription for £5.50 per month, saving £4.40 versus the NHS charge.

How can you save money on Omeprazole 20mg?

Patients in England who pay the prescription charge can switch to a private prescription for Omeprazole 20mg and pay significantly less. Through RepeatsDirect, a qualified pharmacist independent prescriber conducts a short clinical review and issues a private prescription. You pay £5.50 per month — saving £4.40 per month, or £52.80 per year.

OptionPer monthPer year
NHS prescription charge£9.90£118.80
RepeatsDirect (private Rx)£5.50£66.00
Annual PPC (unlimited NHS Rx)£9.54/mo avg£114.50

A PPC is better value if you pay for 12+ items per year. RepeatsDirect is better value if you pay for fewer items or only want to switch the cheapest drugs.

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Frequently asked questions about Omeprazole 20mg