Mirtazapine 45mg: Cost, Savings, and How to Pay Less
Mirtazapine 45mg is the maximum antidepressant dose with least sedation, with a Drug Tariff price of approximately 90p per pack.
How much does Mirtazapine 45mg cost on the NHS?
Mirtazapine 45mg has a Drug Tariff price of approximately 90p for a 28-tablets pack — a full month's supply. Yet NHS patients in England pay a flat £9.90 per item. With 9m items dispensed in 2024/25, Mirtazapine is one of the most prescribed drugs in England. Through RepeatsDirect, patients can access the same medication privately for £5.50/month.
How much does Mirtazapine 45mg actually cost?
The NHS Drug Tariff lists the reimbursement price for Mirtazapine 45mg at approximately 90p per 28-tablets pack. This is the price the NHS pays pharmacies for the drug itself. The NHS prescription charge of £9.90 covers this drug cost plus dispensing fees, administration, and a contribution to NHS services — but for cheap generic drugs, it represents a significant markup.
Drug Tariff cost
90p
per pack
NHS charge
£9.90
1,000% markup
Our price
£5.50
via private Rx
Mirtazapine has approximately 9m items dispensed annually in England (NHSBSA PCA 2024/25).
What is Mirtazapine used for?
Mirtazapine 45mg is the maximum licensed dose, used for patients who have not adequately responded to lower doses. At this dose, the alpha-2 blocking effect is maximised, providing the greatest antidepressant effect with relatively less sedation than at 15mg.
The Drug Tariff price for Mirtazapine 45mg is approximately 90p per 28-tablet pack. The NHS charge of £9.90 is 11 times the drug cost.
RepeatsDirect can supply Mirtazapine 45mg for £5.50 per month via private prescription from our pharmacist independent prescriber.
How can you save money on Mirtazapine 45mg?
Patients in England who pay the prescription charge can switch to a private prescription for Mirtazapine 45mg and pay significantly less. Through RepeatsDirect, a qualified pharmacist independent prescriber conducts a short clinical review and issues a private prescription. You pay £5.50 per month — saving £4.40 per month, or £52.80 per year.
| Option | Per month | Per year |
|---|---|---|
| NHS prescription charge | £9.90 | £118.80 |
| RepeatsDirect (private Rx) | £5.50 | £66.00 |
| Annual PPC (unlimited NHS Rx) | £9.54/mo avg | £114.50 |
A PPC is better value if you pay for 12+ items per year. RepeatsDirect is better value if you pay for fewer items or only want to switch the cheapest drugs.
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